lecture outline: what develops? This chapter highlights what is known about typical and atypical development across the life span, with consideration of neural development as a foundation that interacts with environmental stressors, trauma or disease, or intervention. 6. The most recently investigated field in which both classes of drugs have opposing effects is neuron survival and neurogenesis. - Evaluate theoretical implications for neo-nativist and WS: e.g., brontosaurus, tyranodon, ibex, hippopotamus, bull, yak. At term equivalent age, ten preterm and ten . (Answer under these subtopics: Learning process, developmentally appropriate instruction strategy, modification plan, and accommodation strategies. dr karl wall 2009. human development. Oxford: BPS Blackwell, 2003, 426 pages. Signs and symptoms are frequently subtle in the very old. One of your YouTube videos saved my sons life, he was my first baby and I couldnt tell that he has atypical movement if I didnt see your video. M.W. ( or other specialist. Atypical Child Development Cell duplication is long lasting about 30 hours, after the cells, called embryonic disk, are added quickly and become an organism. abnormal cell division. Chap. Child and Adolescent Psychology provides an accessible and thorough introduction to human development by integrating insights from typical and atypical development. One of your YouTube videos saved my sons life, he was my first baby and I couldnt tell that he has atypical movement if I didnt see your video. How social interactions affect student development and readiness for learning. Charts of speech, language, and hearing milestones from birth to 5. A theory of assisted performance, in P. Light, S. Sheldon, M. Woodhead (eds). By whitelisting SlideShare on your ad-blocker, you are supporting our community of content creators. Chlamydia psittaci. Reference sources 4 Eysenck. Reference sources 2 Sylva, K. and Lunt, I. CHLD 102: Child Growth and Development Developmental Case Study Learning Outcomes 1. Child Development - typical and atypical development - . introduction:. HUMAN SEXUALITY4YR.ppt.pdf from PSYCHOLOGY SOCIAL PSY at Kenyatta University. typical and atypical development fInfancy (Birth to 2 years) (TYPICAL) Infants (two months old) a typical development begin to smile at people Pay attention to faces They can hold head up and begins to push up when lying on tummy Typically play with people and might cry when playing stops They also begins to babble Developmental milestones include physical or behavioral signs of physical, social, and cognitive progress that lead to mastery over one's environment. Psychology and the Teacher. It's called www.HelpWriting.net So make sure to check it out! We've updated our privacy policy. You can learn how to recognize the differences between typical and atypical development. Variation and range in milestones From Table 4 Ages when motor skills are achieved p95 of Herbert, M. (2003) Typical and Atypical Development. You might be concerned if your child is not yet crawling or walking when many peers are already displaying this skill. They are all artistically enhanced with visually stunning color, shadow and lighting effects. And, best of all, it is completely free and easy to use. atypical definition: 1. not having all the characteristics that you would usually expect from a particular group of. - PowerPoint PPT presentation Number of Views: 492 Avg rating:3.0/5.0 Slides: 29 Provided by: psyc72 Category: Tags: atypical | development | puberty less To understand the consequences of prematurity on language perception it is fundamental to determine how atypical early sensory experience affects brain development. dos yr 1 dr karl wall 2010. human development. Oxford: BPS Blackwell. Usually, XX with an SRY gene translocated on one, Sometimes, an XX and XY conceptus fuse or 1 sperm, Several have become pregnant and delivered, Infertile, no puberty, deficits in visuospatial, Treated with GH testosterone for growth, and, Male SRY trumps any number of DAX-1 genes, as, Tall, small testes, breast development, sparse, Learning disabilities, especially for language, Lack of enzyme ? a diagnosis of adh should not be made unless a diagnosis of low grade dcis is being, Atypical Polymyalgia Rheumatica - . 06/06/2023 Online Event. c. Similarities and differences of individuals with and without exceptionalities d. Unique strengths and needs of students with exceptionalities e. The family system 3. This integration cements understanding since the same processes are involved. Dr Karl Wall 2009. One investigator found that 78% of those experiencing AMI reported feeling feverish or sweaty. Toddlers -13-36 months. GA4, GA8 . Learn about the effects on early childhood development. It is based on the belief that it is vital for those training to work with children who have problems to understand what is typical or atypical in children's . Oxford: BPS Blackwell. - Human Growth and Development Lesson 2 Fertilization to Birth First Trimester 4 weeks Heart begins to beat 10 weeks Functioning internal organs & arms, legs - THE DEVELOPMENT OF B-LYMPHOCYTES STAGES IN LIFE CYCLE OF B-LYMPHOCYTES Stage 1 Maturation in bone marrow with development of functional receptors Stage 2 Testing for Chapter 1 Development Across the Lifespan. bc science probe 9 section 4.5 pages 127-129. nondisjunction. TYPICAL AND ATYPICAL DEVELOPMENT. London: Routledge. Communication and Atypical Language Development - Nancy j. aguinaga , ph.d. communication and atypical language, Typical Speech and Language Development: - . Indeed, this happens in very rare cases. death. Principles of Developmental Psychology.Hove: Psychology Press. Do you have PowerPoint slides to share? Am J Ment Retard 1 July 2003; 108 (4): 288289. Variation and range in milestones 3 Ave. 7 mths Ave. 8 mths Ave. 9 mths Crawls 5 mths - 11mths Pulls to a standing position 5 mths - 12mths Uses a pincer grasp 7-10 months Based on Table 4 Ages when motor skills are achieved p95 of Herbert, M. (2003) Typical and Atypical Development. You can learn how to recognize the differences between typical and atypical development. London: Fontana. Death. The PowerPoint PPT presentation: "Atypical Development" is the property of its rightful owner. This concise guide offers an accessible introduction to the development of communication and language in infancy and childhood. Course Hero is not sponsored or endorsed by any college or university. It is useful to share insightful information on Typical Atypical This PPT slide can be easily accessed in standard screen and widescreen aspect ratios. He is constantly showing off things that he has made with his familys new 3D printer. Different factors interplay with each . dr karl wall 2009. human development. Experiments with the amount of force needed to pick up different objects. language development and blindness. Sutherland, P. (1992). He becomes easily bored with new topics in class and then starts to become a distraction to others. Abstract. agency workers casual workers fixed-term workers apprentices volunteers, interns and work, Atypical Meiosis - . These may initially involve nonspecific declines in functional or mental status, anorexia with reduced oral intake, incontinence, falls (Htwe et al., 2007), fatigue, (Hall, 2002), or exacerbation of . Typical development in children gives a generic picture of progress compared to same-age peers. Observes environment from a variety of positions - while lying on back or tummy, sitting, crawling, and standing with assistance. Child Development - typical and atypical development. Donaldson, M. (1978) Childrens Minds. Thorax and the chest wall PPT Jincy Ashish . section 1-1. objectives. ali somily md. Oxford: Blackwell Publishing. Do not sell or share my personal information, 1. Therefore, milestones are generally reported in age ranges, rather than by a specific age. : an American History (Eric Foner), Brunner and Suddarth's Textbook of Medical-Surgical Nursing (Janice L. Hinkle; Kerry H. Cheever), Campbell Biology (Jane B. Reece; Lisa A. Urry; Michael L. Cain; Steven A. Wasserman; Peter V. Minorsky), Biological Science (Freeman Scott; Quillin Kim; Allison Lizabeth), Child and Early Adolescent Development and Psychology, Child and Early Adolescent Development and Psychology Notes, Proposal Argument Final Draft Chavez Ethan ENG106, GCU ELM 200 - Outline and lecture notes from lesson, ELM-200 Chapters Two and Six Discussion Outline, ELM 200 Topic 6-week 6 Discussion Questions 1&2, ELM-210-D-T2-Aligning Standards and Learning Objectives. The term adaptive development refers to the every day living skills a typical human being needs to function. They'll give your presentations a professional, memorable appearance - the kind of sophisticated look that today's audiences expect. You could not be signed in. child development. The SAGE Handbook of Special Education. 40 Cards - 4 Decks - 1 Learner Reference sources 5 Miller, P. H. (2002) Theories of Developmental Psychology (4th edn). Oxford: BPS Blackwell. (Answer under these subtopics: Learning process, developmentally appropriate instruction strategy, modification plan, and accommodation strategies. what drives. Atypical anti psychotic drugs are recommended over typical psychotic . Variation and range in milestones 1 Ave. 3 weeks Ave. 2 months Ave. 4.5 months Holds head steady when held upright (1 week - 4 months) Lying on tummy lifts self by arms 3 weeks - 5 months Rolls from side to back 3 wks - 5 mon. nontuberculous mycobacteria. Interdisciplinary approaches offer the greatest promise for future work with children who have disabilities. Play more with boys toys, less interested in, Normal internal genitalia testes secrete T, MIH, Lack of DHT leads to inadequate masculinization, At puberty, lots of T ? ashley n. lyons, m.ed. Her parents are Spanish-speaking but are not literate in the language. From upper part of Figure 18 p154 of Herbert, M. (2003) Typical and Atypical Development. Rolls from back to side 2-7 months Based on Table 4 Ages when motor skills are achieved p95 of Herbert, M. (2003) Typical and Atypical Development. Childrens Thinking. Appointments 866.588.2264. Infants- birth to 12 months. Description: The PEC Group www.parnell-eng.com parnelltk@gmail.com. Articulate theories of growth, development and learning in all children ages 0-8 years, and demonstrate awareness of these theories as they impact children through adolescence. chapter 2: cognitive development how childrens thinking develops. An emphasis is placed on atypical development associated with . development refers to the biological and psychological changes that The field of study that examines the patterns of - Title: Molecular Pathology Author: user Last modified by: SSC1 Created Date: 11/24/2005 6:32:37 PM Document presentation format: On-screen Show (4:3), Analyzing Atypical Development: Causes and Comorbidities, - Analyzing Atypical Development: Causes and Comorbidities, - Title: Behavioral Observation and Screening in Child Care Author: Andrew Dennard Last modified by: quinna Created Date: 4/5/2006 9:49:00 PM Document presentation format. This could be a sign of a motor or movement disorder. I visited so many doctors to evaluate my sons situation, until I found out that my son needed physical therapy. testes descend, scrotum, Due to mutation in gene for androgen receptor, Do not menstruate or have pubic or underarm hair, Larger in heterosexual men than in women or gay, Same was true in men who did not die of AIDS, Same size in male and female fetuses before day, T surges in males (day 18 of gestation and again, Neurons die in females due to lack of T during, Male and female fetuses have similar SNBs and, Muscles, but not neurons, have androgen receptors, Females lack the T surge, so muscles atrophy. 2. Intellectual Disabilities Developmental Milestones: Physical: Late development with fine and gross motor skills (Children with ID may require support when transitioning from laying down to sitting up). B.F. Skinner (1904 -1990): Child behaviour shaped by how experience is reinforced: Role of reward and punishment > experience conditions behaviour, Child development theories 4 Alfred Bandura (1925 -present): Learning informed by imitation and social observation Role of motivation and inner psychological processes modelling, role models, social learning: Social Learning Theory, Child development theories 5 Lev Vygotsky (1896-1934): Learning interactions as basis of development: Role of social context, language, communication and the mediating influence of others inform a social constructivist development Historical, cultural and social factors inform cognition and development - language is the principal societal tool, Child development theories 6 Jean Piaget (1896 -1980): development seen as: Four, genetically driven, universal and sequential stages of symbol based cognitive development. Human development. what are the, Child Development - . Herbert, M. (2003) Typical and Atypical Development. (Answer under these subtopics: Learning process, developmentally appropriate instruction strategy, modification plan, and accommodation strategies. a. Enjoy access to millions of ebooks, audiobooks, magazines, and more from Scribd. Summaries Date Rating year Ratings Assignments Date Rating year Ratings 18 mths 60 mths: typical development From lower part of Figure 18 p154 of Herbert, M. (2003) Typical and Atypical Development. Specialty Retail uses allowed in LC districts, including retail specialty shops. ), Carl is known as the class clown. Dr Karl Wall 2009. Typical and atypical development : from conception to adolescence Responsibility Martin Herbert. Typical and atypical growth and development b. Etiologies and medical aspects. At that time my son was 6 months old and was not moving as he should. Psychology: A Students Handbook. Middle adulthood. pneumonia caused by atypical, Atypical Mycobacterium - . Early adulthood. The doctor may want to use specialized tests, such as X-rays, magnetic resonance imaging (MRI) , an electroencephalogram (EEG) , or laboratory tests to gather information about your childs brain, spine, or musculoskeletal system. a case, Atypical nervous system development such as cerebral palsy - . 3-5 years old. We've encountered a problem, please try again. 2nd Edition. Dimensions of change : Physical Sensory Motor Social Emotional Cognitive Reproductive Experiential. Neurological maturation (historic view) Systems model based on biomechanical theory More ecological approach Includes influence of the environment The task at hand Psychological processes Motivation Personality Interaction between musculoskeletal and neurological maturation, Gross motor development Muscle control progresses: Cephalo-caudal From gross motor to fine motor Proximal to distal Reflex to intentionality Simple to complex Head control Supine to prone Shoulder control Allows pivoting and turning over by 4th or 5th month Trunk control Sit up independently at 6 months Get into and out of sit at 8 months Hip control Lower body control Refinement, Windows of achievement Sit without support: 4 9 months Stand with assistance: 5 11 months, Hand and knee crawling: 5 13months Walking with assistance: 6 14 months, Standing alone: 7 17 months Walking alone: 9 17 months, Motor development: Fine Motor Skills Eye contact Facial expression Reaching Grasping Palmar Pincer Handedness Reflection of hemisphere dominance, Language Development Communication Speech sounds Language Communicating idea, wish, desire, need, emotion Receptive language: usually higher ability What is understood Expressive language: usually lower than receptive language What is said Innate ability for language Acquired in universal pattern Modeled by more competent speakers, repeated practice of sounds and words, Language Form Three aspects of language Phonology: study of speech sounds Syntax: rules of language, grammar Morphological development: word structure and word parts, such as prefixes and suffixes, Phonological development Cooing - vowel sounds Babbling - C/V (consonant/vowel) Sound production D,t,k,m,h (8 months) G,n,b W,s P,s,k,z (two years) F, ts, j, l, r, pw, bw Fw, kw, pl, nts, nd, ps, ts Dz, sp, st, sn, sl Tw, sk, sm, bl, kl, gl, br, tr, dr, kr, gr (4 years) V, fr, sr, pr, fl (5 years) Ma-ma, da-da, pa-pa nonspecificially Mama dada papa specifically Single words, objects Two-word sentences after approximately 30 50 words, Syntax Morphological Development Morpheme: smallest part of a word that has meaning Mean length of utterance (MLU) More than three, have morphological inflections in phrases Simple two-word sentences include noun-verb, verb-noun, and noun-noun Wh questions are challenging Who, what, where, when, how, why, Expressive language Semantics What words mean Overextension All blue cars are Mommys car Underextension Categories are too narrow: only my red blanket is my blankie; all other blankies are something else, Factors Affecting Language Development Developmental disabilities Cleft lip/cleft palate Oral-structural anomalies associated with Down syndrome Influence phonological production Cerebral palsy Reduced respiratory capacity Autism All areas of language affected Language deficits often inherited (50%) Culture and sociocultural factors influence rate of language acquisition Parenting influences language acquisition Motherese is correlated to language development Children with disabilities may require structured opportunities to facilitate language development With children whose language is developing typically, Cognitive development How we acquire knowledge Early experiences are critical to acquiring knowledge and sculpt: Perception Selective attention Learning Memory Language Personality Cognition Brain is plastic and can create alternative routes to adjust to auditory and visual experiences Repeated exposure to stimuli molds a response and pathways that have not been able to respond, drop out and die, Theories of cognition Preoperational Representational thought Symbolic ability Egocentrism Irreversibility Concrete operations Decentration Reversibility Logic Conservation Relational thinking (shorter, longer) Hierarchical relationships Formal operations Flexible thinking Abstract thinking Piaget: Developmental approach Four distinct stages: Sensorimotor Six substages Reflex activity Primary circular reactions Secondary circular reactions Coordination of secondary schemes Tertiary circular reactions Mental combinations Object permanence Attachment Strong indicator of memory in infants, Social emotional development Emergence of individual emotions and personality is result of and influence on dynamic relationships with others and the environment Adapting to community norms that govern living within a society Social development: Observable behavior Emotional development: Takes place under the skin Influenced by language and cognitive development Influences on social-emotional development Heredity Culture Economics Community, Social emotional development (cont) Maternal stress and anxiety increases cortisol that crosses the placenta that affect hormonal and brain development When infants experience prolonged subtle forms of emotional deprivation (when mothers are depressed) they experience a dampening of their own emotions Fail to gain weight Lethargic Development is compromised Environmental factors that place parents at risk of being inadequate nurturers of secure attachment: Substance abuse Child abuse Underage pregnancy Low socioeconomic status Economic stressors Poverty Infant prematurity Overcrowding Absent fathers, Social emotional development (cont) Parenting affects development: Emotional resiliency develops when mothers are primarily positive Young children learn to regulate their emotions and their impulses Coercive parenting patterns lead to harsh and inconsistent consequences, leading to later social problems and emotional depression, Vygotsky: Crisis of Three: Defiant Behavior Negativism Stubbornness Obstinancy Willfulness Protest Devaluation Calls stupid or dumb Despotism Wants complete power over those around, Children with disabilities Impairment in one area can significantly alter the ability of child to initiate or respond to interactions that build or maintain social relationships, Social play Play is the medium that infants and toddlers acquire and execute social relationships Play is the work of young children Economic stability in a family contributes to more social contacts, Types of play (cognitive) Solitary play Isolation and independence Spectator play (onlooker play Parallel play Associative play Lacks organization Toys shared without regard for groups wishes Cooperative Play Games with rules 6 years of age Children learn: Truth Honesty Fair play Self-control Leadership skills, Self-help development AKA Adaptive skills Independent feeding Dressing Toileting Personal responsibilities, Independent eating and drinking skills Sucking reflex Solid pureed foods Table foods Dramatic change around 8 months Drink from cup Feed themselves finger foods Age 2 independent eaters and drinkers Use of spoon More narrow range of food preferences, Dressing skills Pull socks off Assist in dressing Pull pants up and down Zippers Dress self by 3 years, Toileting skills Muscle control not fully developed until 2 years of age Bowel movements may cause fear in child Not unusual to still use diapers at three years of age, especially if any other delays exist, Personal responsibility Pick up their toys Routines Wipe up spills Clear the table Dirty clothes in a hamper, Children With Disabilities Chapter 4: Birth Defects and Prenatal Diagnosis, Birth defects and prenatal diagnosis Upon completion of this chapter, the student will: Understand the uses and limitations of noninvasive prenatal maternal blood screening for birth defects Be knowledgeable regarding the indications for, and limitations of, first- and second-trimester evaluation of birth defects using the techniques of ultrasound, fetal MRI and ECG Be aware of techniques of amniocentesis and chorionic villus sampling to determine when these invasive diagnostic tests may be indicated Be familiar with alternative reproductive techniques (IVF) and understand when couples might benefit from such technologies Learn about new noninvasive prenatal diagnosis technologies being explored Understand the psychosocial needs of families who are at risk, Birth defects and prenatal diagnosis 3% of births result in a child with a birth defect or genetic disorder Circumstances can increase risk Most affected newborns are born to couples unaware they are at risk and have no family history, Birth Defects and Prenatal Diagnosis Noninvasive prenatal maternal blood screening First-semester evaluation of birth defects Ultrasonogram Fetal magnetic resonance imaging Echocardiography Second-trimester evaluation of birth defects Invasive diagnostic tests Amniocentesis Chorionic villus sampling Alternative reproductive techniques In vitro fertilization Psychosocial needs of families at risk for having children with genetic disorders or birth defects, Prenatal diagnosis and screening Gives parents opportunity to gain information about fetus Gives parents opportunity to examine a range of family planning options Screening can occur before pregnancy or during pregnancy, Genetic Assessment 20,000 genetic disorders have been identified Genetic testing available for 2,000 genetic disorders Ethnic background Specific ethnic backgrounds have higher chance of certain gene mutations associated with genetic disorders Review of medical and pregnancy history Extended family history Presence of family birth defects and genetic disorders Unexplained infant deaths Recurrent pregnancy losses Maternal medication use Occupational or teratogen exposure Carrier screening Autosomal recessive High morbidity (disease) and mortality (death), Genetic assessment Genetics Home Reference National Library of Medicine supported database National Organization for Rare Disorders (NORD) www.rarediseases.org Genetic Alliance A clearinghouse for information and support groups for genetic disorders www.geneticalliance.org, Screening evaluations during pregnancy First Trimester Ultrasound Establishes viability Determines number of fetuses Confirm placenta position 11 14 weeks can measure nuchal translucency (transparency of the fluid-filled cavity at the nape of the fetuss neck Increased nuchal translucency is associated with adverse outcomes Congenital heart disease Fetal anomalies Fetal death Down syndrome: abnormal Doppler flow in ductus venosus and tricuspid regurgitation (signs of congenital heart disease) Maternal serum (blood) screening Screening for disorders common in specific ethnic groups Cystic fibrosis Sickle cell anemia Tay Sachs Chorionic villus sampling, Screening evaluations during pregnancy First-Trimester Maternal serum screening Free beta hCG and PAPP-A at 10 14 weeks combined with ultrasound identifies 87% fetuses with Down syndrom <5% false-positive Extreme variations of free beta hCG and PAPP-A can indicate: Low birth weight Stillbirth Fetal loss Early delivery Cell-free DNA in plasma of pregnant woman Fetal DNA can be detected in background of maternal DNA, assessment fetal chromosomal abnormalities Further work needs to be done before technique is widely available for clinical use, Screening evaluations during pregnancy First trimester Chorionic villus sampling Performed 10 12 weeks Use ultrasound to guide suction through small catheter passed through cervix or aspiration via needle inserted through abdominal wall and uterus Minute biopsy of chorion (outermost membrane surrounding embryo) Consists of rapidly dividing cells Detects chromosomal abnormalities Use for enzyme assay for inborn errors of metablism Use for molecular DNA analysis to identify specific mutations that cause genetic diseases Does not detect neural tube defects such as spina bifida Safest invasive prenatal diagnostic procedure 1% risk of precedure-related pregnancy loss If performed after 10 weeks, no increased risk of causing fetal anomaly, Screening evaluations during pregnancy Second Trimester Maternal serum screening Screening sensitivity is improving but is not diagnostic AFP (low), hCG, uE3, and Inhibin A has improved detection of Down syndrome, 80% with 5% false-positive rate When combined with other indicators including maternal age, weight, race, diabetic status and number of fetuses, can assess risk for: Neural tube defects (spina bifida and anencephaly) Abdominal wall defects (gastroschisis and omphalocele) Trisomy 18 AFP high levels can be associated with multiple fetuses, gestational age greater than anticipated or higher risk for preterm delivery, stillbirth, or intrauterine loss If serum screen suggests increased risk for Down syndrome, trisomy 18 or trisomy 13, diagnostic testing is recommended, Screening Evaluations During pregnancy Second-trimester Ultrasound 18 20 weeks detects 60% of major structural anomalies Can be used to diagnose neural tube defects and abdominal wall defects (previously screened for by second-trimester serum testing) High resolution ultrasound revolutionized identification of fetal anatomic abnormalities Can be used to diagnose: Facial clefts Renal anomalies Skeletal anomalies Hydrocephalus Heart defects Other malformations Does not replace amniocentesis and CVS, Screening evaluations during pregnancy Second trimester Amniocentesis Performed at 15 18 weeks Ultrasound used to guide procedure Needle inserted below mothers umbilicus, through abdominal and uterine walls 1 2 ounces of amniotic fluid aspirated Fetal urine replaces fluid in 24 hours Pregnancy loss when performed before 14 weeks increases, higher rates of musculoskeletal deformities (club foot), and greater risk of fluid leakage CVS preferred first trimester, Screening evaluations during pregnancy Magnetic resonance imaging Used approximately 17 weeks No sedation No known risks at this time MRI of central nervous system can demonstrate presence: Corpus callosum Chiari malformation of the brain Cause of enlarged ventricles (hydrocephalus) Ultrasound identifies the risk, MRI confirms http://www.youtube.com/watch?v=TiG2nbsc-gc http://www.youtube.com/watch?v=SFY5COYwlXU https://www.youtube.com/watch?v=ijhLPWBzziA https://www.youtube.com/watch?v=w7rh_mdL71Q https://www.youtube.com/watch?v=aHEi_31IYhg https://www.youtube.com/watch?v=RcKfgBqU0H0, Screening Evaluations During pregnancy Second trimester Fetal Echocardiography Congenital heart disease (CHD) most common anatomical abnormality, contributing to 1/3 of congenital anomaly deaths in childhood Targeted ultrasound performed 18 22 weeks Three- and four-dimensional studies 10 15% of infants with CHD have underlying chromosomal abnormality, Diagnostic testing of fetal cells CVS Amniocentesis To test for chromosomal analysis Biochemical analysis For inborn errors of metabolism or DNA analysis For fragile X syndrome or cystic fibrosis Fluorescent in situ hybridization (FISH) Short pieces of DNA (called DNA probe) of known sequence can attach to a unique region on a chromosome FISH used to identify specific chromosomes or indicate small deletions of a defined region of a specific chromosome FISH used to detect microdeletions Discover of certain CHDs should prompt consideration of FISH analysis to detect 22q11.2 deletion associated with VCFS/DiGeorge Syndrome, 1 in 4,000 live births, The most sophisticated prenatal diagnostic technology cannot guarantee the birth of a typical child. 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